medinfoАктуальные проблемы теоретической и клинической медициныActual Problems of Theoretical and Clinical Medicine2790-12892790-1297Казахстанско-Российский медицинский университет10.64854/2790-1289-2026-52-2-13medinfo-1023Research ArticleОБЗОР ЛИТЕРАТУРЫREVEWSВЗАИМОСВЯЗЬ МИНЕРАЛЬНОГО ОБМЕНА И КЛИНИКО-МЕТАБОЛИЧЕСКИХ ПОКАЗАТЕЛЕЙ У ЛИЦ С МЕТАБОЛИЧЕСКИМ СИНДРОМОМMINERAL METABOLISM RELATIONSHIP WITH CLINICAL AND METABOLIC INDICATORS IN INDIVIDUALS WITH METABOLIC SYNDROMEhttps://orcid.org/0009-0002-5797-8379АнарбаеваА. А.AnarbayevaA. A.asel.anarbayeva@ayu.edu.kzhttps://orcid.org/0000-0002-9120-8565СадыковаК. Ж.SadykovaK. Zh.karlygash.sadykova@ayu.edu.kzhttps://orcid.org/0000-0003-2139-3221НускабаеваГ. О.NuskabaevaG. O.nuskabaeva.gulnaz@ayu.edu.kzhttps://orcid.org/0000-0001-5341-7211НұрдиновН. С.NurdinovN. S.nursultan.nurdinov@ayu.edu.kzhttps://orcid.org/0000-0003-4141-574XЖаналиеваМ. К.ZhanaliyevaM. K.marinazhmk@mail.ruhttps://orcid.org/0000-0002-7519-479XТатыкаеваУ. Б.TatykayevaU. B.ugilzhan.tatykayeva@ayu.edu.kzМеждународный казахско-турецкий университет имени Ходжа Ахмеда ЯсавиКазахстанKhoja Akhmet Yassawi International Kazakh-Turkish UniversityKazakhstanМедицинский университет АстаныКазахстанMedical University AstanaKazakhstanМеждународный казахско-турецкий университет имени Ходжа Ахмеда ЯсавиКазахстанKhoja Akhmet Yassawi International Kazakh-Turkish UniversityKazakhstan202603072026021023Copyright © Анарбаева А., Садыкова К., Нускабаева Г., Нұрдинов Н., Жаналиева М., Татыкаева У., 20262026Анарбаева А., Садыкова К., Нускабаева Г., Нұрдинов Н., Жаналиева М., Татыкаева У.Anarbayeva A., Sadykova K., Nuskabaeva G., Nurdinov N., Zhanaliyeva M., Tatykayeva U.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://kazrosmedjournal.krmu.edu.kz/jour/article/view/1023Актуальность

Актуальность. Метаболический синдром  является одной из ключевых проблем современного здравоохранения, поскольку он значительно повышает риск развития сахарного диабета 2-го типа, сердечно-сосудистых заболеваний и нарушений липидного обмена. Одним из важных, но недостаточно изученных факторов, влияющих на формирование и тяжесть метаболического синдрома, является минеральный обмен, включая уровни кальция, магния и фосфора. Дисбаланс этих минералов может нарушать чувствительность к инсулину, способствовать воспалительным процессам и оказывать влияние на липидный и углеводный обмен. 

Цель исследования

Цель исследования. Обобщить и критически оценить современные данные о взаимосвязи минерального обмена (кальция, магния, фосфора, паратиреоидного гормона и витамина D) с клиническими и метаболическими проявлениями метаболического синдрома у взрослых.

Методы и материалы

Методы и материалы. Проведен структурированный поиск литературы в базах данных PubMed, Scopus и Google Scholar. В обзор преимущественно были включены публикации, опубликованные в период с января 2018 по март 2026 года. При необходимости для описания физиологических механизмов и формирования теоретической основы исследования дополнительно использовались более ранние фундаментальные публикации.

Результаты

Результаты. Анализ литературы показал, что нарушения минерального обмена тесно связаны с развитием и клинико-метаболическими проявлениями метаболического синдрома. Наиболее убедительные данные получены в отношении дефицита магния, а также нарушений обмена кальция, фосфора, паратиреоидного гормона и витамина D, связанных с инсулинорезистентностью и другими метаболическими нарушениями

Выводы

Выводы. Проведенный литературный обзор подтверждает, что нарушения минерального обмена, включая уровни сывороточного кальция, магния и фосфора, тесно связаны с клинико-метаболическими проявлениями метаболического синдрома.

Relevance

Relevance. Metabolic syndrome is a cluster of interconnected metabolic abnormalities characterized by central obesity, hypertension, dyslipidemia, and impaired glucose metabolism. One important but under-studied factor influencing the development and severity of metabolic syndrome is mineral metabolism, including calcium, magnesium, and phosphorus levels. An imbalance of these minerals can disrupt insulin sensitivity, promote inflammatory processes, and affect lipid and carbohydrate metabolism.

Objective

Objective. To summarize and critically evaluate current evidence on the relationship between mineral metabolism (calcium, magnesium, phosphorus, parathyroid hormone, and vitamin D) and the clinical and metabolic manifestations of metabolic syndrome in adults.

Materials and methods

Materials and methods. A structured literature search was conducted in PubMed, Scopus, and Google Scholar. The review primarily included studies published between January 2018 and March 2026, while earlier landmark publications were included when necessary to provide physiological background.

Нәтижелері

Нәтижелері. Әдебиеттерді талдау минералдық алмасу бұзылыстарының метаболизмдік синдромның дамуы және оның клиникалық-метаболикалық көріністерімен тығыз байланысты екенін көрсетті. Ең сенімді деректер магний тапшылығына, сондай-ақ кальций, фосфор, паратиреоидты гормон және D витамині алмасуының бұзылыстарына қатысты алынды, олар инсулинге төзімділікпен және басқа да метаболикалық бұзылыстармен байланысты болды.

Conclusions

Conclusions. The literature review confirms that mineral metabolism disorders, including serum calcium, magnesium, and phosphorus levels, are closely related to the clinical and metabolic manifestations of metabolic syndrome.

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The authors declare that there are no conflicts of interest present.