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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medinfo-128</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>АКТУАЛЬНОСТЬ ИЗУЧЕНИЯ КЛИНИКО-ДИНАМИЧЕСКИХ ОСОБЕННОСТЕЙ ШИЗОФРЕНИИ, ОСЛОЖНЕННОЙ ПРИЕМОМ СОВРЕМЕННЫХ ПСИХОАКТИВНЫХ ВЕЩЕСТВ</article-title><trans-title-group xml:lang="en"><trans-title>RELEVANCE OF STUDYING THE CLINICAL AND DYNAMIC FEATURES OF SCHIZOPHRENIA COMPLICATED BY NEW DRUGS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8548-3464</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Редько</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Redko</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший преподаватель</p></bio><bio xml:lang="en"><p>senior lecturer</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3477-2565</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ешимбетова</surname><given-names>С. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeshimbetova</surname><given-names>S. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Professor</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НУО «Казахстанско-Российский медицинский университет»</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>NEI «Kazakh-Russian Medical University»</institution><country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>01</day><month>11</month><year>2022</year></pub-date><volume>0</volume><issue>3</issue><fpage>47</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Редько М.С., Ешимбетова С.З., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Редько М.С., Ешимбетова С.З.</copyright-holder><copyright-holder xml:lang="en">Redko M.S., Yeshimbetova S.Z.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/128">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/128</self-uri><abstract><p>Шизофрения - одно из социально значимых, инвалидизирующих заболеваний. Около одного процента населения мира, в том числе и в Казахстане, страдает шизофренией. Начало заболевания, чаще всего, происходит в молодом возрасте-от 18 до 25 лет.Употребление психоактивных веществ может быть началом формирования манифестного эндогенного психоза, что может быть интегрировано в эндогенный процесс и может изменять клиническую картину заболевания. Это значительно усложняет диагностический процесс для практикующих врачей и затрудняет решение социально-реабилитационных вопросов для больных, страдающих коморбидными психическими расстройствами в виде шизофрении и психическими и поведенческими расстройствами, вызванными употреблением психоактивных веществ.Цель исследования: определить актуальность исследования у больных шизофренией, осложненной зависимостью от новых лекарственных препаратов.</p></abstract><trans-abstract xml:lang="en"><p>Schizophrenia is one of the socially significant, disabling diseases. About one percent of the world's population, including in Kazakhstan, suffers from schizophrenia. The start of the disease, most often happens at a young age - from 18 to 25 years old, a young age is also the beginning of manifestations of deviant processes in the form of use of various psychoactive substances. The use of psychoactive substances can be the starting mechanism for the formation of manifest endogenous psychosis, can be integrated into the endogenous process and alter the clinical picture of the disease, which complicates the diagnostic process for practicing physicians and complicates the solution of social and rehabilitation issues for patients suffering from comorbid mental disorders in the form of schizophrenia and mental and behavioral disorders caused by the use of psychoactive substances.The purpose: define relevance in patients with schizophrenia complicated by addiction to new drugs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>шизофрения</kwd><kwd>новые психоактивные вещества</kwd><kwd>коморбидные расстройс тва</kwd></kwd-group><kwd-group xml:lang="en"><kwd>schizophrenia</kwd><kwd>new psychoactive substances</kwd><kwd>comorbid disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Altynbekov K.S. 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