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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2023-1-93-98</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-297</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVEWS</subject></subj-group></article-categories><title-group><article-title>ЭВОЛЮЦИЯ ЛЕЧЕНИЯ ТУБЕРКУЛЕЗА В ИНДИИ ОТ САНАТОРНО КУРОРТНОГО ЛЕ ЧЕНИЯ К ПЕРСОНАЛИЗИРОВАННОЙ МЕДИЦИНЕ</article-title><trans-title-group xml:lang="en"><trans-title>THE EVOLUTION OF TUBERCULOSIS TREATMENT IN INDIA FROM SANATORIUMS TO PERSONALIZED MEDICINE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2724-2328</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Singh</surname><given-names>A.</given-names></name><name name-style="western" xml:lang="en"><surname>Singh</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Aryan Singh, студент 2 курса, Факультета «Общая медицина»</p><p>Алматы</p></bio><bio xml:lang="en"><p>Aryan Singh, 2nd year of student, Faculty of General Medicine</p><p>Almaty</p></bio><email xlink:type="simple">nauka@medkrmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НУО «Казахстанско-Российский медицинский университет»<country>Казахстан</country></aff><aff xml:lang="en">NEI «Kazakh-Russian Medical University»<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>27</day><month>04</month><year>2023</year></pub-date><volume>0</volume><issue>1</issue><fpage>93</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Singh A., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Singh A.</copyright-holder><copyright-holder xml:lang="en">Singh A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/297">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/297</self-uri><abstract><p>Туберкулез (ТБ) – тяжелое инфекционное заболевание, поражающее людей на протяжении веков. Лечение туберкулеза значительно эволюционировало с годами: от использования санаториев в качестве основного метода лечения до внедрения антибиотиков и появления персонализированной медицины. Санатории были популярны в конце 19 - начале 20 веков, но их доступность и стоимость были ограничены. Открытие и разработка антибиотиков, таких как стрептомицин и изониазид, привели к широкому внедрению антибиотиков в качестве основного средства лечения туберкулеза. Персонализированная медицина — это новый подход, ориентированный на конкретные потребности каждого пациента посредством генотипирования и индивидуальных схем лечения. Будущее лечения туберкулеза может заключаться в индивидуальных подходах. Данная статья представляет собой обзор литературы по указанной теме на основе тематических исследований.</p></abstract><trans-abstract xml:lang="en"><p>Tuberculosis (TB) is a serious infectious disease that has affected humans for centuries. The treatment of TB has evolved significantly over the years, from the use of sanatoriums as the primary treatment method to the introduction of antibiotics and the emergence of personalized medicine. Sanatoriums were popularized in the late 19th and early 20th centuries but were limited in their accessibility and cost. The discovery and development of antibiotics, such as streptomycin and isoniazid, led to the widespread adoption of antibiotics as the primary treatment for TB. Personalized medicine is a new approach that targets the specific needs of each patient through genotyping and individualized drug regimens. The future of TB treatment may lie in individualized, personalized approaches. This article is a literature review on the mentioned topic based on Case Studies.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез (ТБ)</kwd><kwd>санатории</kwd><kwd>изониазид</kwd><kwd>вакцина</kwd><kwd>НИСТ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tuberculosis</kwd><kwd>sanatoriums</kwd><kwd>isoniazid</kwd><kwd>vaccines</kwd><kwd>NTEP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization (WHO). Global Tuberculosis Report 2021. https://www.who.int/publications/i/item/9789240037021.</mixed-citation><mixed-citation xml:lang="en">World Health Organization (WHO). Global Tuberculosis Report 2021. https://www.who.int/publications/i/item/9789240037021.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Migliori G.B., Sotgiu G., Gandhi N.R., et al. Drug resistance in tuberculosis. Cold Spring Harbor perspectives in medicine, 2015, 5(9), a017800. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556232/.</mixed-citation><mixed-citation xml:lang="en">Migliori G.B., Sotgiu G., Gandhi N.R., et al. Drug resistance in tuberculosis. Cold Spring Harbor perspectives in medicine, 2015, 5(9), a017800. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556232/.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Zumla A., George A., Sharma V., et al. The WHO 2014 Global tuberculosis report—further to go. The Lancet Global Health, 2015, 3(1), e10-e12. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(14)70361-4/fulltext.</mixed-citation><mixed-citation xml:lang="en">Zumla A., George A., Sharma V., et al. The WHO 2014 Global tuberculosis report—further to go. The Lancet Global Health, 2015, 3(1), e10-e12. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(14)70361-4/fulltext.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization (WHO). Treatment of Tuberculosis: Guidelines for Treatment of Drug-Susceptible Tuberculosis and Patient Care, 2017 Update. https://www.who.int/tb/publications/2017/dstb_guidance_2017/en/.</mixed-citation><mixed-citation xml:lang="en">World Health Organization (WHO). Treatment of Tuberculosis: Guidelines for Treatment of Drug-Susceptible Tuberculosis and Patient Care, 2017 Update. https://www.who.int/tb/publications/2017/dstb_guidance_2017/en/.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Johnson J.L., Neumann G., MacKenzie T., et al. Optimizing treatment for drug-resistant tuberculosis. PLoS medicine, 2006, 3 (3), e120. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030120.</mixed-citation><mixed-citation xml:lang="en">Johnson J.L., Neumann G., MacKenzie T., et al. Optimizing treatment for drug-resistant tuberculosis. PLoS medicine, 2006, 3 (3), e120. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030120.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Centers for Disease Control and Prevention (CDC). Treatment of Tuberculosis. CDC, 2022. https://www.cdc.gov/tb/topic/treatment/default.htm.</mixed-citation><mixed-citation xml:lang="en">Centers for Disease Control and Prevention (CDC). Treatment of Tuberculosis. CDC, 2022. https://www.cdc.gov/tb/topic/treatment/default.htm.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization (WHO). The End TB Strategy. WHO, 2015. https://www.who.int/tb/post2015_strategy/en/.</mixed-citation><mixed-citation xml:lang="en">World Health Organization (WHO). The End TB Strategy. WHO, 2015. https://www.who.int/tb/post2015_strategy/en/.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
