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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2022-2-1518</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-4</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>АНАЛИЗ КОГНИТИВНОГО ДЕФИЦИТА ПРИ ШИЗОФРЕНИИ И СОВРЕМЕННЫЕ МЕТОДЫ ЛЕЧЕНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>ANALYSIS OF COGNITIVE DEFICITS IN SCHIZOPHRENIA AND MODERN TREATMENT METHODS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2816-7083</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучкоров</surname><given-names>У. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuchkarov</surname><given-names>U. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>candidate of medicine</p></bio><email xlink:type="simple">kuchkarovu76@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5581-6005</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ходжаева</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khodzhaeva</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Professor</p></bio><email xlink:type="simple">nazira.xodjaeva@tma.uz</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Бухарский государственный медицинский институт<country>Узбекистан</country></aff><aff xml:lang="en">Bukhara State Medical Institute<country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Ташкентская медицинская академия<country>Узбекистан</country></aff><aff xml:lang="en">Tashkent Medical Academy<country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2022</year></pub-date><volume>0</volume><issue>2</issue><fpage>15</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кучкоров У.И., Ходжаева Н.И., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Кучкоров У.И., Ходжаева Н.И.</copyright-holder><copyright-holder xml:lang="en">Kuchkarov U.I., Khodzhaeva N.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/4">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/4</self-uri><abstract><p>Нами исследовано 62 пациента с диагнозом параноидная шизофрения, проходивших лечение в Бухарском областном психоневрологическом диспансере. Проанализирована связь между клинико-психопатологическими характеристиками и когнитивными расстройствами. Анализ социального статуса и нарушений социального функционирования больных, страдающих шизофренией показывает нарушение когнитивных функции,  больных. Включение в алгоритм лечения больных основной группы атипичных нейролептиков, достоверно улучшает когнитивные функции не усиливая продуктивную симптоматику.</p></abstract><trans-abstract xml:lang="en"><p>We examined 62 patients with a diagnosis of paranoid schizophrenia who were undergoing treatment at the Bukhara Regional Psychoneurological Dispensary. The relationship between clinical and psychopathological characteristics and cognitive functions was analyzed. Analysis of the social status and disorders of social functioning of patients suffering from schizophrenia shows a violation of cognitive function, which affects the social adaptation of patients. The inclusion of atypical antipsychotics in the treatment algorithm of patients in the main group significantly improves cognitive functions without increasing productive symptoms</p></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивный дефицит</kwd><kwd>шизофрения</kwd><kwd>клинико-социологические параметры</kwd><kwd>качества жизни</kwd><kwd>лечения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive deficit</kwd><kwd>schizophrenia</kwd><kwd>clinical and sociological parameters</kwd><kwd>quality of life</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Зайцева Ю.С. Первый психотический эпизод: пяилетнее катамнестическое клинико-нейропсихологичекое исследование: Дисс. канд. мед. наук. М.: 2010. 223 с.</mixed-citation><mixed-citation xml:lang="en">Zajceva Ju.S. 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