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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2024-1-12-17</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-405</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVEWS</subject></subj-group></article-categories><title-group><article-title>Спекл-трекинговая эхокардиография как мощный диагностический инструмент ранней субклинической кардиотоксичности у онкологических пациентов во время и после химиотерапии</article-title><trans-title-group xml:lang="en"><trans-title>Speckle-Tracking Echocardiography as a powerful diagnostic tool of early subclinical cardiotoxicity in cancer patients during and after chemotherapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0491-5334</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акбалаева</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Akbalaeva</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Б. А. Акбалаева, </p><p>город Ош.</p></bio><bio xml:lang="en"><p>Osh city, </p><p>begimai_a@yahoo.com</p><p>Akbalaeva Begimai Akbalaevna,</p><p>Osh city.</p></bio><email xlink:type="simple">begimai_a@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8587-705X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Райимбек уулу</surname><given-names>Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Raiimbek uulu</surname><given-names>N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Н. Райимбек уулу,</p><p>город Ош.</p></bio><bio xml:lang="en"><p>Raimbek uulu Nurlan,</p><p>Osh city.</p></bio><email xlink:type="simple">nurlanraimbekuulu@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8905-9807</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярлыоглуес</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Yarlioglues</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>М. Ярлыоглуес, </p><p>Анкара</p></bio><bio xml:lang="en"><p>Yarlioglues (Yaroglues) Mikail – Phd, Associate Professor, </p><p>Ankara.</p></bio><email xlink:type="simple">drmikailyar@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Ошский государственный университет<country>Кыргызстан</country></aff><aff xml:lang="en">Osh State University<country>Kyrgyzstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Анкарский учебно-исследовательский госпиталь<country>Турция</country></aff><aff xml:lang="en">Ankara Teaching and Research Hospital<country>Turkey</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>19</day><month>05</month><year>2024</year></pub-date><volume>0</volume><issue>1</issue><fpage>24</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Акбалаева Б.А., Райимбек уулу Н., Ярлыоглуес М., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Акбалаева Б.А., Райимбек уулу Н., Ярлыоглуес М.</copyright-holder><copyright-holder xml:lang="en">Akbalaeva B.A., Raiimbek uulu N., Yarlioglues M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/405">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/405</self-uri><abstract><p>Цель. В данной статье обсуждается важность ранней диагностики кардиотоксичности, возникающей в результате химиотерапевтического лечения онкологических заболеваний.Материалы и методы. Кардиотоксичность, побочный эффект химиотерапии, может проявляться на разных этапах лечения и значительно снижать качество жизни пациентов, увеличивая риск развития сердечно-сосудистых заболеваний и смертности. В работе подчеркивается, чтоспекл-трекинговая эхокардиография является новаторским методом оценки механики миокарда,позволяющим выявлять субклинические изменения сердечной функции на ранних стадиях. Авторы рассматривают принципы работы STE, ее преимущества перед традиционными методами диагностики, а также важность интеграции данного метода в клиническую практику для оптимизациилечебных стратегий онкологических пациентов.Выводы. Статья призывает к дальнейшему изучению STE и подчеркивает ее потенциальнуюроль в улучшении прогноза и качества жизни пациентов, подвергающихся химиотерапии. </p></abstract><trans-abstract xml:lang="en"><p>Purpose. This article discusses the importance of early diagnosis of cardiotoxicity resulting fromchemotherapy treatment of cancer.Мaterials and methods. Cardiotoxicity, a side effect of chemotherapy, can manifest at various stagesof treatment and significantly reduce patients' quality of life, increasing the risk of developing cardiovascular diseases and mortality. The work emphasizes that speckle-tracking echocardiography is an innovativemethod for assessing myocardial mechanics, allowing for the detection of subclinical changes in cardiacfunction at early stages. The authors examine the principles of speckle-tracking echocardiography, its advantages over traditional diagnostic methods, and the importance of integrating this method into clinicalpractice to optimize treatment strategies for cancer patients.Conclusions. The article calls for further study of speckle-tracking echocardiography and highlightsits potential role in improving prognosis and quality of life for patients undergoing chemotherapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>спекл-трекинговая эхокардиография</kwd><kwd>кардиотоксичность</kwd><kwd>химиотерапия</kwd><kwd>миокардиальная механика</kwd><kwd>сердечная функция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>speckle-tracking echocardiography</kwd><kwd>cardiotoxicity</kwd><kwd>chemotherapy</kwd><kwd>myocardial mechanics</kwd><kwd>cardiac function</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шуйкова К. В., Емелина Е. И., Гендлин Г. Е., Сторожаков Г. И. Кардиотоксичность современных химиотерапевтических препаратов // Атмосфера. Новости кардиологии. – 2012. – № 3. – С. 9-19.</mixed-citation><mixed-citation xml:lang="en">Shuykova, K. V., Emelina, E. 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