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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2024-2-20-32</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-432</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Исследование распространенности нарушений функции почек у урбанизированного и сельского населения (на примере города Алматы и Алматинской области)</article-title><trans-title-group xml:lang="en"><trans-title>Estimate the prevalence of impaired renal function to residents of Almaty and Almaty region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9202-7451</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тундыбаева</surname><given-names>М. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Tundybayeva</surname><given-names>M. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тундыбаева Мейрамгуль Капсиметовна – кардиолог, доктор медицинских наук, профессор, доцент кафедры кардиологии</p><p>Алматы</p></bio><bio xml:lang="en"><p>Tundybayeva Meiramgul Kapsimetovna – cardiologist, doctor of Medical Sciences, Professor, Associate Professor of the Department of Cardiology</p><p>Almaty</p></bio><email xlink:type="simple">mira_2828@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7452-5625</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джунусбекова</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Junusekova</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джунусбекова Гульнара Алдешовна – кардиолог, доктор медицинских наук, профессор, доцент кафедры кардиологии</p><p>Алматы</p></bio><bio xml:lang="en"><p>Dzhunusbekova Gulnara Aldeshovna – cardiologist, doctor of Medical Sciences, Professor, Associate Professor of the Department of Cardiology</p><p>Almaty</p></bio><email xlink:type="simple">gulnara_1010@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2489-8276</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беркинбаев</surname><given-names>С. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Berkinbayev</surname><given-names>S. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беркинбаев Салим Фахатович – кардиолог, доктор медицинских наук, профессор, заведующий кафедрой кардиологии</p><p>Алматы</p></bio><bio xml:lang="en"><p>Berkinbayev Salim Fakhatovich – cardiologist, doctor of Medical Sciences, Professor, Head of the Department of Cardiology</p><p>Almaty</p></bio><email xlink:type="simple">s.berkinbaev@kaznmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5828-3742</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухтарханова</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukhtarkhanova</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мухтарханова Диляра Мухтаровна – кардиолог, докторант PhD 3 курса, кафедра кардиологии</p><p>Алматы</p></bio><bio xml:lang="en"><p>Mukhtarkhanova Dilyara Mukhtarovna – cardiologist, PhD student of the 3rd Year, Department of Cardiology</p><p>Almaty</p></bio><email xlink:type="simple">dilyaramukhtarkhan@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3880-5798</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Багланова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Baglanova</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Багланова Лязат Сайлаубековна – кардиолог, магистр медицинских наук, кандидат PhD НУО «Казахстанско-Российский медицинский университет»;</p><p>ассистент кафедры кардиологии</p><p>г. Алматы</p></bio><bio xml:lang="en"><p>Baglanova Lyazat Sailaubekovna – cardiologist, master of Medical Sciences, PhD candidate NEI «Kazakh-Russian Medical University»;</p><p>assistant of the Department of Cardiology</p><p>Almaty</p></bio><email xlink:type="simple">lyazat.begaidaro@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0628-9215</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самитова</surname><given-names>С. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Samitova</surname><given-names>S. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самитова Сабина – врач общей практики, кардиолог-резидент 3 курса</p><p>Алматы</p></bio><bio xml:lang="en"><p>Samitova Sabina – general practitioner, resident cardiologist of the 3rd year</p><p>Almaty</p></bio><email xlink:type="simple">sabinasamitova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НАО «Казахский национальный медицинский университет имени С. Д. Асфендиярова»<country>Казахстан</country></aff><aff xml:lang="en">NpJSC «Kazakh national medical university named after S. D. Asfendiyarov»<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>07</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>20</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тундыбаева М.К., Джунусбекова Г.А., Беркинбаев С.Ф., Мухтарханова Д.М., Багланова Л.С., Самитова С.Б., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Тундыбаева М.К., Джунусбекова Г.А., Беркинбаев С.Ф., Мухтарханова Д.М., Багланова Л.С., Самитова С.Б.</copyright-holder><copyright-holder xml:lang="en">Tundybayeva M.K., Junusekova G.A., Berkinbayev S.F., Mukhtarkhanova D.M., Baglanova L.S., Samitova S.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/432">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/432</self-uri><abstract><p>Цель. Изучить распространенность нарушения функции почек по данным определения скорости клубочковой фильтрации среди жителей города Алматы и Алматинской области.Материалы и методы. обследовано 1575 взрослых лиц в возрасте от 18 до 69 лет, определение скорости клубочковой фильтрации проводилось по формуле CKD-EPI, включающей пол, возраст пациента и концентрацию креатинина в сыворотке крови, кроме того в анализ были включены половозрастные, социальные характеристики, а также факторы риска сердечно-сосудистых заболеваний: повышение общего холестерина; холестерина липопротеинов низкой плотности;холестерина липопротеинов высокой плотности, триглицериды; определяли степень абдоминального ожирения, глюкоза плазмы натощак.Результаты. Скорость клубочковой фильтрации была оценена у 1553 респондентов, что составило 97,2 % случая наблюдения, среднее значение скорость клубочковой фильтрации в целом по изучаемой популяции составило 101,9 ± 18,2 мл/мин/1,73 м2, лица с высокой/оптимальной скоростью клубочковой фильтрации (76,7 %) и лица со сниженной скоростью клубочковой фильтрации (23,2 %), Среди респондентов с дисфункцией почек по данным скорости клубочковойфильтрации, проживающих в городе Алматы и области достоверно чаще встречались женщины (90 %), лица старшего возраста (37,1 %), жители города (72,3 %), а также респонденты, страдающие абдоминальным ожирением (75 %) и артериальной гипертонией высокой степени (25,88 %).Заключение. При оценке функции почек, определенной по скорости клубочковой фильтрации, определенной по формуле CKD-EPI, KDIGO, 2024 среди жителей города Алматы и Алматинскойобласти, сниженная ренальная функция определялась у 23,2 % респондентов, при этом в этой группе достоверно чаще встречались лица женского пола, старшей возрастной группы (60-69 лет),жители города, среди кардиометаболических факторов риска значимыми являлись абдоминальное ожирение, высокая степень артериальной гипертонии.</p></abstract><trans-abstract xml:lang="en"><p>Purpose. To study the prevalence of renal dysfunction (NFP) as determined by glomerular filtration rate (CKD-EPI, KDIGO, 2024) among the residents of Almaty and Almaty region.The materials and methods. 1575 adults aged 18 to 69 years, determining RF performed formula CKDEPI, including sex, age of the patient and the concentration of creatinine in the serum, except in the analysisincluded age and gender, social characteristics, and risk factors for cardiovascular disease: increased total cholesterol (TC); Low-density lipoprotein (LDL); High density lipoprotein cholesterol, triglycerides; determined by the degree of abdominal adiposity, fasting plasma glucose.The results.GFR was estimated at 1 553 respondents, which accounted for 97.2 % of cases of observation, mean GFR in the whole study population was 101,9 ± 18,2 ml / min / 1.73 m2, those with high / optimal SCF (76.7 %) and persons with reduced GFR (23.2 %) among respondents with renal dysfunction according to GFR, living in Almaty and the region women were significantly more likely (90%), older persons (37.1% ), residents of the city (72.3%) and respondents who suffer from joint-stock company (75 %) and a high degree of hypertension (25.88 %).The conclusion. In assessing renal function, defined by GFR determined by the formula CKD-EPI, KDIGO, 2024 among residents of Almaty and Almaty region, decreased renal function was determined in 23.2 % of respondents, while in this group were significantly more frequent faces female, older age group (60-69 years), residents of the city, among the important cardiometabolic risk factors were abdominal obesity, high degree of hypertension.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>скорость клубочковой фильтрации</kwd><kwd>нарушения функции почек</kwd><kwd>Алматы</kwd><kwd>Алматинская область</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glomerular filtration rate</kwd><kwd>renal dysfunction</kwd><kwd>Almaty</kwd><kwd>Almaty region</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. 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