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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2024-2-66-72</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-436</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Болезнь Паркинсона: краткий обзор и клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>Parkinson's disease: a brief overview and clinical observation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4912-4229</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каржаубаева</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karzhaubayeva</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каржаубаева Манчук Амантаевна – старший преподаватель кафедры неврологии</p><p>Алматы</p></bio><bio xml:lang="en"><p>Karzhaubaeva Manchuk Amantaevna – senior lecturer at the Department of Neurology</p><p>Almaty</p></bio><email xlink:type="simple">manshuk_md90@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-1933-0550</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сапарғалиева</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Sapargalieva</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сапарғалиева Ақмарал Болатбекқызы – резидент-невролог 2 курс</p><p>Алматы</p></bio><bio xml:lang="en"><p>Sapargalieva Akmaral Bolatbekkyzy – resident neurologist 2nd year</p><p>Almaty</p></bio><email xlink:type="simple">bolatbekovna.1993@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-1980-5917</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рысбаева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Rysbaeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рысбаева Айдана Сагидуллаевна – резидент-невролог 2 курс</p><p>Алматы</p></bio><bio xml:lang="en"><p>Rysbaeva Aidana Sagidullayevna – resident neurologist 2nd year</p><p>Almaty</p></bio><email xlink:type="simple">ailuna17@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НУО «Казахстанско-Российский медицинский университет»<country>Казахстан</country></aff><aff xml:lang="en">«Kazakh-Russian medical university» NEI<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>07</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>67</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каржаубаева М.А., Сапарғалиева А.Б., Рысбаева А.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Каржаубаева М.А., Сапарғалиева А.Б., Рысбаева А.С.</copyright-holder><copyright-holder xml:lang="en">Karzhaubayeva M.A., Sapargalieva A.B., Rysbaeva A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/436">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/436</self-uri><abstract><p>Болезнь Паркинсона является вторым по распространенности нейродегенеративным заболеванием, и согласно прогнозам, ее распространенность удвоится в течение следующегопоколения. Тем не менее, своевременная диагностика болезни Паркинсона остается сложной задачей, а выявление самых ранних стадий заболевания является серьезной неудовлетвореннойпотребностью.В данной работе мы описали клинический случай диагностики классической формы болезни Паркинсона у больного пожилого возраста, поздней диагностики болезни Паркинсона в отделенииневрологии центральной городской клинической больницы города Алматы.На основании клинических и инструментальных данных выставлен диагноз: Болезнь Паркинсона, акинетико-ригидная форма, без постуральной неустойчивости. Стадия 4 по Хен и Яру.Представленный клинический пример демонстрирует классический вариант болезни Паркинсона. Постепенное развитие симптомов, наличие типичных моторных и немоторных проявлениий у пациента пожилого возраста позволили клинически установить диагноз болезнь Паркинсона.</p></abstract><trans-abstract xml:lang="en"><p>Parkinson's disease is the second most common neurodegenerative disease, and its prevalence is projected to double over the next generation. Nevertheless, timely diagnosis of Parkinson's disease remainsa difficult task, and the identification of the earliest stages of the disease is a serious unmet need. In this paper, we described a case of diagnosis of the classic form of Parkinson's disease in an elderly patient.In this paper, we describe a clinical case of diagnosing the classic form of Parkinson's disease in an elderly patient with late diagnosis at the Department of Neurology at the Central City Clinical Hospital inAlmaty. Based on clinical and instrumental data, the diagnosis was established as: Parkinson's disease, akinetic-rigid form, without postural instability, Stage 4 according to the Hen and Yaru scale.The presented clinical example demonstrates a classic case of Parkinson's disease. The gradual development of symptoms, along with the presence of typical motor and non-motor manifestations in an elderly patient, allowed for the clinical diagnosis of Parkinson's disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Болезнь Паркинсона</kwd><kwd>тремор</kwd><kwd>мышечная ригидность</kwd><kwd>дисфагия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Parkinson's disease</kwd><kwd>tremor</kwd><kwd>muscle rigidity</kwd><kwd>dysphagia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Goldman S. M., Tanner C. Etiology of Parkinson's's disease. In: Jankovic J., Tolosa E., editors. 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