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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2025-2-13-21</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-597</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ПРЕДОПЕРАЦИОННОЙ ТРАНСКАТЕТЕРНОЙ АРТЕРИАЛЬНОЙ ЭМБОЛИЗАЦИИ НА КРОВОПОТЕРЮ И ВРЕМЯ ОПЕРАЦИИ ПРИ ЭНДОСКОПИЧЕ- СКОЙ ТРАНСНАЗАЛЬНОЙ РЕЗЕКЦИИ ЮВЕНИЛЬНОЙ АНГИОФИБРОМЫ</article-title><trans-title-group xml:lang="en"><trans-title>IMPACT OF PREOPERATIVE TRANSCATHETER ARTERIAL EMBOLIZATION ON BLOOD LOSS AND SURGERY TIME DURING ENDOSCOPIC TRANSNASAL RESECTION OF JUVENILE ANGIOFIBROMA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-6025-5724</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурмагамбетова</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurmagambetova</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нурмагамбетова Айжан</p><p>Астана</p></bio><bio xml:lang="en"><p>Nurmagambetova Aizhan A.</p><p>Astana</p></bio><email xlink:type="simple">aizhan.nurmagambetova.99@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7274-8101</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сагандыкова</surname><given-names>Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sagandykova</surname><given-names>N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сагандыкова Назым – доктор медицинских наук, MMed, PhD</p><p>Астана</p><p>телефон: +7 701 8888 542</p></bio><bio xml:lang="en"><p>Sagandykova Nazym S. – MD, MMed, PhD</p><p>Astana</p><p>phone: +7 701 8888 542</p></bio><email xlink:type="simple">doctor.ent.alm@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2185-6345</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бекпан</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekpan</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бекпан Алмат – Кандидат медицинских наук</p><p>Астана</p></bio><bio xml:lang="en"><p>Bekpan Almat Zh. – Ph.D</p><p>Astana</p></bio><email xlink:type="simple">almat-bekpanov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6458-6712</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ауталипов</surname><given-names>Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Autalipov</surname><given-names>D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ауталипов Дархан</p><p>Астана</p></bio><bio xml:lang="en"><p>Autalipov Darkhan Kh.</p><p>Astana</p></bio><email xlink:type="simple">darkhanautalipov88@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1244-8673</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бауржан</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Baurzhan</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бауржан Мадина – PhD</p><p> Астана</p><p>телефон: 87772375738</p></bio><bio xml:lang="en"><p>Baurzhan Madina – PhD</p><p>Astana</p><p>phone: 87772375738</p></bio><email xlink:type="simple">madina_baurzhan@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Корпоративный фонд «Университетский медицинский центр»<country>Казахстан</country></aff><aff xml:lang="en">Corporate Fund «University Medical Center»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научно-исследовательский институт курортологии и медицинской реабилитации; Астанинский медицинский университет<country>Казахстан</country></aff><aff xml:lang="en">Research Institute of Balneology and Medical Rehabilitation; Astana Medical University<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>06</day><month>07</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>13</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нурмагамбетова А., Сагандыкова Н., Бекпан А., Ауталипов Д., Бауржан М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Нурмагамбетова А., Сагандыкова Н., Бекпан А., Ауталипов Д., Бауржан М.</copyright-holder><copyright-holder xml:lang="en">Nurmagambetova A., Sagandykova N., Bekpan A., Autalipov D., Baurzhan M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/597">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/597</self-uri><abstract><p>Ювенильная назофарингеальная ангиофиброма является наиболее распространенной доброкачественной опухолью носоглотки у подростков мужского пола, часто проявляющейся агрессивной локальной инвазией и тяжелым, потенциально опасным для жизни носовым кровотечением. Ее высоковаскулярная природа осложняет хирургическую резекцию, делая предоперационную трансартериальную эмболизацию важным шагом для снижения интраоперационной кровопотери и улучшения результатов. Оценка эффективности различных методов эмболизации имеет решающее значение для оптимизации эндоскопического хирургического лечения и минимизации осложнений. Актуальность исследования обусловлена постоянной необходимостью повышения хирургической безопасности и эффективности, особенно с учетом того, что эндоскопические подходы становятся стандартом лечения при лечении этой сложной опухоли.</p><sec><title>Цель</title><p>Цель: определить влияние предоперационной транскатетерной артериальной эмболизации на интраоперационную кровопотерю и время операции при эндоскопической трансназальной резекции ювенильной носоглоточной ангиофибромы.</p></sec><sec><title>Методы и материалы</title><p>Методы и материалы: был проведен ретроспективный анализ тридцати пациентов-подростков мужского пола, прошедших хирургическое лечение в Университетском медицинском центре с февраля 2014 года по декабрь 2023 года. Когорта была разделена на две группы: те, кому была проведена предоперационная транскатетерная артериальная эмболизация (n=19), и те, кому она не была проведена (n=11). Сравнивались такие характеристики, как кровопотеря и продолжительность операции.</p></sec><sec><title>Результаты</title><p>Результаты: у пациентов, которым была проведена предоперационная транскатетерная артериальная эмболизация, наблюдалось значительное снижение интраоперационной кровопотери на всех стадиях ювенильной носоглоточной ангиофибромы. Хотя предоперационная транскатетерная артериальная эмболизация сократила время, необходимое для операции, результаты не были статистически значимыми.</p></sec><sec><title>Выводы</title><p>Выводы: предоперационная транскатетерная артериальная эмболизация значительно улучшает результаты хирургического вмешательства, успешно снижая интраоперационное кровотечение во время резекции ювенильной носоглоточной ангиофибромы.</p></sec></abstract><trans-abstract xml:lang="en"><p>Juvenile nasopharyngeal angiofibroma is the most common benign tumor of the nasopharynx in adolescent males, often presenting with aggressive local invasion and severe, potentially life‑threatening epistaxis. Its highly vascular nature complicates surgical resection, making preoperative transarterial embolization an important step to reduce intraoperative blood loss and improve outcomes. Evaluating the effectiveness of different embolization techniques is critical for optimizing endoscopic surgical treatment and minimizing complications. This study was driven by an ongoing need to improve surgical safety and efficiency, especially as endoscopic approaches become the standard of care in managing this challenging tumor.</p><sec><title>The purpose of the study</title><p>The purpose of the study. Тo determine the effect of preoperative transcatheter arterial embolization on intraoperative blood loss and surgery time for endoscopic transnasal resection of juvenile nasopharyngeal angiofibroma.</p></sec><sec><title>Methods and materials</title><p>Methods and materials. A retrospective analysis was conducted on thirty adolescent male patients who received surgical treatment at the University Medical Center from February 2014 to December 2023. The cohort was divided into two groups: those who underwent preoperative transcatheter arterial embolization (n = 19) and those who did not (n = 11). The characteristics compared included blood loss and the duration of surgery.</p></sec><sec><title>Results</title><p>Results. Patients who underwent preoperative transcatheter arterial embolization experienced a significant reduction in intraoperative blood loss across all stages of juvenile nasopharyngeal angiofibroma. Although preoperative transcatheter arterial embolization reduced the time required for surgery, the results were not statistically significant.</p></sec><sec><title>Conclusions</title><p>Conclusions. Preoperative transcatheter arterial embolization significantly enhances surgical outcomes by effectively reducing intraoperative bleeding during the resection of juvenile nasopharyngeal angiofibroma.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ангиофиброма носоглотки</kwd><kwd>предоперационная транскатетерная артериальная эмболизация</kwd><kwd>объем кровотечения</kwd><kwd>время операции</kwd><kwd>рецидив</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nasopharyngeal angiofibroma</kwd><kwd>preoperative transcatheter arterial embolization</kwd><kwd>bleeding volume</kwd><kwd>surgery time</kwd><kwd>recurrence</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bora M., Das A. 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DOI: https://doi.org/10.1007/s00270-023-03483-1.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
