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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2021-22831</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-61</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>КЛИНИКО-МОРФОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА COVID-19 АССОЦИИРОВАННЫХ ПНЕВМОНИЙ В ЗАВИСИМОСТИ ОТ РЕЗУЛЬТАТА ПЦР ИССЛЕДОВАНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF COVID-19 ASSOCIATED PNEUMONIA DEPENDING ON THE RESULTS OF PCR STUDIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharova</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жангелова</surname><given-names>Ш. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhangelova</surname><given-names>Sh. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куттыгожин</surname><given-names>Е. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuttygozhin</surname><given-names>E. Zh.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шумкова</surname><given-names>Э. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shumkova</surname><given-names>E. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6335-6125</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Славко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Slavko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Ass. Professor</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НАО «КазНМУ им. С.Д. Асфендиярова»<country>Казахстан</country></aff><aff xml:lang="en">«KazNMU named after S.D. Asfendiyarov»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="en">«KazNMU named after S.D. Asfendiyarov»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">КГП на ПХВ «Городское патолого-анатомическое бюро» УОЗ<country>Казахстан</country></aff><aff xml:lang="en">«City Pathology and Anatomical Bureau» of the DPH<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">НАО «КазНМУ им. С.Д. Асфендиярова<country>Казахстан</country></aff><aff xml:lang="en">«KazNMU named after S.D. Asfendiyarov»<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2022</year></pub-date><volume>0</volume><issue>2</issue><fpage>28</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гончарова А.В., Жангелова Ш.Б., Куттыгожин Е.Ж., Шумкова Э.Н., Славко Е.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Гончарова А.В., Жангелова Ш.Б., Куттыгожин Е.Ж., Шумкова Э.Н., Славко Е.А.</copyright-holder><copyright-holder xml:lang="en">Goncharova A.V., Zhangelova S.B., Kuttygozhin E.Z., Shumkova E.N., Slavko E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/61">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/61</self-uri><abstract><p>При проведении анализа 65-ти летальных исходов от COVID-19 пневмоний: у мужчин 63%, женщин 37%, чаще отмечалась двухсторонняя полисегментарная пневмония. На вскрытии специфических макроскопических изменений не выявлено. Микроскопические изменения в легких у умерших как с ПЦР положительным результатом, так и ПЦР отрицательным результатом, характеризовались развитием респираторного дистресс-синдрома. Фиброз в паренхиме легкого был уже отмечен на ранних сроках, тогда как в поздних сроках отмечался более выраженный, с присоединением гнойного экссудата и грибкового поражения</p></abstract><trans-abstract xml:lang="en"><p>An analysis of 65 deaths from COVID-19 pneumonia was carried out: 63% for men, 37% for women. Bilateral polysegmental pneumonia was more common. Autopsy revealed no specific macroscopic changes. Microscopic changes in the lungs of those who died with a positive PCR result and a negative PCR result were characterized by the development of respiratory distress syndrome. Fibrosis in the lung parenchyma was noted already in the early stages, and at later stages it was more pronounced with the addition of purulent exudate and fungal lesions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>пневмония</kwd><kwd>патологическая анатомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>pneumonia</kwd><kwd>pathological anatomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Патологическая анатомия при COVID-19. Атлас. Под редакцией О.В. Зайратьянца, Москва, 2020, 116 с.</mixed-citation><mixed-citation xml:lang="en">Патологическая анатомия при COVID-19. Атлас. Под редакцией О.В. Зайратьянца, Москва, 2020, 116 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Беляков Н.А., Рассохин В.В., Ястребова Е.Б. 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