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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24412/2790-1289-2021-13840</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-80</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVEWS</subject></subj-group></article-categories><title-group><article-title>ПОРАЖЕНИЕ ПЕЧЕНИ ПРИ СOVID-19</article-title><trans-title-group xml:lang="en"><trans-title>LIVER INJURY IN COVID - 19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полукчи</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Polukchi</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абуова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Abuova</surname><given-names>G. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6335-6125</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Славко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Slavko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сарыпбекова</surname><given-names>Л. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarypbekova</surname><given-names>L. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5695-5290</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касымова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasymova</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">«Южно-Казахстанская медицинская академия»<country>Казахстан</country></aff><aff xml:lang="en">South Kazakhstan Medical Academy<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">АО «Казахский медицинский университет непрерывного образования»<country>Казахстан</country></aff><aff xml:lang="en">Kazakh Medical university of сontinuing education<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>21</day><month>10</month><year>2022</year></pub-date><volume>0</volume><issue>1</issue><fpage>38</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Полукчи Т.В., Абуова Г.Н., Славко Е.А., Сарыпбекова Л.Л., Касымова Т.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Полукчи Т.В., Абуова Г.Н., Славко Е.А., Сарыпбекова Л.Л., Касымова Т.В.</copyright-holder><copyright-holder xml:lang="en">Polukchi T.V., Abuova G.N., Slavko E.A., Sarypbekova L.L., Kasymova T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/80">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/80</self-uri><abstract><p>В декабре 2019 года в городе Ухань, Китай была впервые зарегистрирована вспышка ранее неизвестной пневмонии, вызванная новым коронавирусом SARS-CoV-2. В настоящее время COVID-19 рассматривается как системное заболевание с поражением различных органов, в том числе и печени. Однако механизм повреждения печени при COVID-19 является недостаточно изученным. Отмечается высокая летальность пациентов с поражением печени и сопутствующим COVID-19, что указывает на неблагоприятный исход заболевания.</p></abstract><trans-abstract xml:lang="en"><p>An outbreak of previously unknown pneumonia caused by the novel coronavirus SARS-CoV-2 was first reported in Wuhan, China in December 2019. Currently, COVID-19 is considered a systemic disease with damage to various organs including the liver. However, the mechanism of liver damage in COVID - 19 is not well understood. There is a high mortality rate in patients with liver damage and concomitant COVID-19 which indicates an unfavorable outcome of the disease</p></trans-abstract><kwd-group xml:lang="ru"><kwd>заболевание</kwd><kwd>вызванное новым коронавирусом</kwd><kwd>поражение печени</kwd><kwd>хронические вирусные гепатиты</kwd><kwd>цирроз печени</kwd><kwd>печеночная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>disease caused by a novel coronavirus</kwd><kwd>liver damage</kwd><kwd>chronic viral hepatitis</kwd><kwd>liver cirrhosis</kwd><kwd>liver failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Clinical characteristics of coronavirus disease 2019 in China. Guan W.J., Ni Z.Y., Hu Y., et al. N Engl J Med. 2020; 382:1708–1720.</mixed-citation><mixed-citation xml:lang="en">Clinical characteristics of coronavirus disease 2019 in China. 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