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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medinfo</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальные проблемы теоретической и клинической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Actual Problems of Theoretical and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2790-1289</issn><issn pub-type="epub">2790-1297</issn><publisher><publisher-name>Казахстанско-Российский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.64854/2790-1289-2025-50-4-04</article-id><article-id custom-type="elpub" pub-id-type="custom">medinfo-854</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ПРОГНОЗИРОВАНИЕ РИСКА ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА НА ОСНОВЕ НЕЛИНЕЙНОГО АНАЛИЗА ВАРИАБЕЛЬНОСТИ СЕРДЕЧНОГО РИТМА ПО ДАННЫМ НОСИМЫХ УСТРОЙСТВ</article-title><trans-title-group xml:lang="en"><trans-title>PREDICTION OF ISCHEMIC HEART DISEASE RISK BASED ON NONLINEAR ANALYSIS OF HEART RATE VARIABILITY FROM WEARABLE DEVICE DATA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-0429-7919</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кожамбердиева</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozhamberdiyeva</surname><given-names>M. I.</given-names></name></name-alternatives><email xlink:type="simple">kozhamberdiyeva.m@outlook.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4584-885X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раушанова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Raushanova</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">Aizhan.Raushanova@kaznu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6767-1699</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдрахманова</surname><given-names>З.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdrakhmanova</surname><given-names>Z.</given-names></name></name-alternatives><email xlink:type="simple">Zinat.Abdrakhmanova@kaznu.edu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0365-0979</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оракбай</surname><given-names>Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Orakbay</surname><given-names>L.</given-names></name></name-alternatives><email xlink:type="simple">l.orakbai@medkrmu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5020-7179</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тулеков</surname><given-names>Ж. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Tulekоv</surname><given-names>Zh. D.</given-names></name></name-alternatives><email xlink:type="simple">d.zhangir@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-5510-3590</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байдаулетова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Baydauletova</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">baidaulet123@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7043-8206</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дуйсенов</surname><given-names>Е. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Duysenov</surname><given-names>Ye. E.</given-names></name></name-alternatives><email xlink:type="simple">y.y.duisenov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">«Казахский национальный университет имени Аль-Фараби»<country>Казахстан</country></aff><aff xml:lang="en">Al-Farabi Kazakh National University<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">НУО «Казахстанско-Российский медицинский университет»<country>Казахстан</country></aff><aff xml:lang="en">Kazakhstan-Russian Medical University<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>53</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кожамбердиева М., Раушанова А., Абдрахманова З., Оракбай Л., Тулеков Ж., Байдаулетова А., Дуйсенов Е., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Кожамбердиева М., Раушанова А., Абдрахманова З., Оракбай Л., Тулеков Ж., Байдаулетова А., Дуйсенов Е.</copyright-holder><copyright-holder xml:lang="en">Kozhamberdiyeva M., Raushanova A., Abdrakhmanova Z., Orakbay L., Tulekоv Z., Baydauletova A., Duysenov Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://kazrosmedjournal.krmu.edu.kz/jour/article/view/854">https://kazrosmedjournal.krmu.edu.kz/jour/article/view/854</self-uri><abstract><sec><title>Ведение</title><p>Ведение.Ишемическая болезнь сердца является одной из ведущих причин смертности во всем мире, что подчеркивает актуальность внедрения доступных и неинвазивных методов скрининга среди населения. Исследование было направлено на оценку возможности использования параметров вариабельности сердечного ритма, регистрируемых с помощью носимого фотоплетизмографического устройства, для стратификации риска ишемической болезни сердца.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В ходе работы было разработано носимое IoT‑устройство «Zhurek», надеваемое на палец и основанное на технологии фотоплетизмографии; устройство в режиме реального времени вычисляет показатели вариабельности сердечного ритма. Показатели «Zhurek» сравнивались с данными трехканального холтеровского мониторирования электрокардиографии, а к данным ангиографически подтвержденных пациентов и здоровых добровольцев были применены алгоритмы машинного обучения.</p></sec><sec><title>Результаты</title><p>Результаты. Отклонения измерений нового устройства по сравнению с холтеровской электрокардиографией находились в клинически приемлемых пределах; параметры вариабельности сердечного ритма, в особенности мощность в низкочастотном диапазоне и возраст пациента, были идентифицированы как ключевые диагностические признаки для выявления ишемической болезни сердца.</p></sec><sec><title>Заключение</title><p>Заключение. Устройство «Zhurek» может быть использовано для масштабной стратификации риска ишемической болезни сердца и способствует переходу системы здравоохранения от ожидания манифестации заболевания к проактивной, профилактически ориентированной модели.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Ischemic heart disease is one of the leading causes of mortality worldwide, highlighting the importance of implementing accessible and non-invasive screening tools at the population level. This study aimed to assess the feasibility of using heart rate variability parameters obtained from a wearable photoplethysmography-based device to evaluate the risk of ischemic heart disease.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A finger-worn IoT device called «Zhurek» was developed, based on photoplethysmography technology and capable of calculating real-time heart rate variability indices. The measurements obtained from «Zhurek» were compared with data from three‑lead Holter electrocardiographic monitoring, and machine learning algorithms were applied to datasets collected from angiographically confirmed patients and healthy volunteers.</p></sec><sec><title>Results</title><p>Results. The deviations between the new device measurements and Holter electrocardiography remained within clinically acceptable limits; heart rate variability parameters, particularly low-frequency power, and patient age were identified as key diagnostic indicators for detecting ischemic heart disease.</p></sec><sec><title>Conclusion</title><p>Conclusion. The «Zhurek» device is suitable for large-scale ischemic heart disease risk stratification and may facilitate a shift in healthcare from a reactive, symptom-driven approach to a proactive, prevention-oriented model.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>вариабельность сердечного ритма</kwd><kwd>фотоплетизмография</kwd><kwd>сердечно сосудистые заболевания</kwd><kwd>машинное обучение.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic heart disease</kwd><kwd>heart rate variability</kwd><kwd>photoplethysmography</kwd><kwd>cardiovascular diseases</kwd><kwd>machine learning</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. (2024). Cardiovascular diseases (CVDs) [Electronic resource]. 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