MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN AND ADOLESCENTS TEMPORARILY ASSOCIATED WITH COVID-19: CLINICAL AND LABORATORY FEATURES

Сoronavirus infection (COVID-19) is a new, changing disease; several strains of COVID-19 mutated virus have already been reported. In children there have been described cases of acute disease with signs of Kawasaki disease and toxic shock syndrome, hyperreactive inflammation leading to multiple organ failure and shock [3; 4; 5]. This variant of the clinical course is referred to as multisystem inflammatory syndrome (MIS) in children and adolescents, temporarily associated with COVID-19. We analyzed the case histories of 14 children hospitalized at Children's Clinical Hospital №2 Almaty with the substantiation of a diagnosis of MIS temporarily associated with COVID-19. Clinical and laboratory features of this condition in children were determined. The average age was 5.5 years. By severity of condition, half of the children (50%) were admitted to intensive care unit. The examined children had symptoms corresponding to WHO criteria of MIS diagnosis - rash, abdominal syndrome (abdominal pain), diarrhea, vomiting. All patients had a significant increase in D-dimer from 430 to 6960 ng/ml.

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