Optimization of treatment of urethritis in patients in the long-term period after urethroplasty

   The article presents the results of the use of electroactivated sodium chloride solutions in the treatment of inflammatory diseases of the urethra, as well as after reconstructive plastic surgery on the urethra in men, an assessment of the effectiveness of the use of therapeutic electroactivated aqueous solutions of sodium chloride "anolyte" and "catholyte" is given. Clinical observations have shown the special effectiveness of the consistent use of therapeutic solutions, contributing to the rapid sanitation of the urethra due to their antiseptic, biostimulating, regenerative effect. A necessary condition for persistence is certain biological properties of the microorganism and the defectiveness of the host's protection, which causes bacterial carrier (persistence of pathogens) and chronization of the inflammatory process (frequent relapses of the disease). By reducing virulence or isolating themselves in foci of local immunodeficiency, bacteria can evade human protection factors. The suppression of host defense factors is due to an increase in the virulent properties of bacteria or as a result of dissemination in an immunocompromised organism. The high adaptability of microorganisms to constantly changing conditions of existence is especially evident in antibiotic therapy – whole classes of antibiotics are devalued due to the selection of resistant strains of microorganisms.

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