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BUFFER SYSTEMS OF THE BODY

https://doi.org/10.24412/2790-1289-2022-3-1722-2026

Abstract

A large number of acidic foods is formed in the human body during the metabolism during the day. The main products of metabolism in the cell are acids that dissociate with the release of [H+] ions, but due to buffer systems, acidification of the intracellular medium does not occur. As a result of oxidative processes, volatile carbonic acid and non-volatile acids are formed in tissues, such as sulfuric acid (during the cleavage of methionine and cystine), uric acid (during the cleavage of nucleoproteins), free fatty acids of various molecular weights, as well as inorganic phosphates. During the day, up to 2-3 liters of hydrochloric acid are formed in the gastric mucosa.
Maintaining the constancy of the pH of the blood, interstitial and cellular sectors is ensured by buffer systems that maintain the pH at the optimal level for the function of organs and tissues

About the Author

N. V. Leontyeva
«I.I. Mechnikov North-Western State Medical University»
Russian Federation

MD, Professor



References

1. Bagrov Ja.Ju., Manusova N.B. Generalizovannye oteki. Patogenez i lechenie. // Nefrologija i dializ. 2011. № 4. T.11. S.388-395.

2. Gorn M.M., Hejtc U.I. Vodno-jelektrolitnyj i kislotnoosnovnoj balans. M.: Izd.: «BINOM. Laboratorija znanij», 2009, 359 str

3. Muhin N.A., Kustova T.S. Znachenie natrijureticheskih peptidov v ocenke vodno-solevogo obmena pri hronicheskoj bolezni pochek // Ter. arhiv. 2014. № 1. T.86. S.95-102.

4. Natochin Ju.V. Klirens osmoticheski svobodnoj i svobodnoj ot natrija vody: klinicheskoe znachenie. // Nefrologija.2012. № 2. T.16. S.9.16.

5. Nefrologija. Nacional'noe rukovodstvo // Pod red. N.A. Muhina. – M.: GJeOTAR-Media, 2016. - 597 s.

6. Shejman D.A. Patofiziologija pochki. M.: Binom.2010. 206 s.

7. Bajmakanova G.E. Interpretacija pokazatelej gazov arterial'noj krovi. // Pul'monologija i allergologija. 2013. № 2. S.42-45.

8. Litvickij P.F. Narushenija kislotno-osnovnogo sostojanij. // Voprosy sovremenno pediatrii. 2011. T.10. № 1. S.83-92.

9. Golub I.E., Netjosin E.S., Sorokina L.V. Narushenija kislotno-osnovnogo sostojanija i vodno-jelektrolitnogo obmena. Irkutsk. 2015. 43 s.

10. Kajukov I.G., Dobronravov V.A., Kucher A.G. i dr. Pochechnye tubuljarnye acidozy v praktike vzroslogo nefrologa. Soobshhenie 1. Rol' pochek reguljacii kislotno-osnovnogo gomeostaza. // Nefrologija. 2013. T.17. № 1. S.20-41.

11. Malyshev V. D. Kislotno-osnovnoe sostojanie i vodnojelektrolitnyj balans v intensivnoj terapii – 2005. 267 s.


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For citations:


Leontyeva N.V. BUFFER SYSTEMS OF THE BODY. Actual Problems of Theoretical and Clinical Medicine. 2022;(3):20-26. (In Russ.) https://doi.org/10.24412/2790-1289-2022-3-1722-2026

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ISSN 2790-1289 (Print)
ISSN 2790-1297 (Online)