Dynamics of changes in biochemical blood parameters in colon cancer against the background of viral carriage

Relevance. Currently, about one million new cases of colon cancer are registered annually in the world, which are the cause of death in half of patients.
The aim of the study was to determine changes in blood biochemical parameters in colon cancer in patients with persistent DNA / RNA viruses.
Materials and methods. The material for the study was blood serum samples from patients with an established diagnosis of cancer. The study shows that prolonged contact with viral DNA / RNA results in persistent biochemical changes in the large intestine, mainly with prolonged persistence of Epstein-Barr virus and cytomegalovirus DNA. The most dynamic indicators in the serum of the subjects were enzymes, creatinine, bilirubin, albumin, triglycerides, gamma-glutamyltransferase, trace elements and immunoglobulins.
Results. Overall, the indicators of total protein, urea, cholesterol, high-density lipoproteins and lowdensity lipoproteins were relatively stable. Reliable dependences of biochemical parameters with the viral DNA
present were established: the DNA of the Epstein-Barr virus and cytomegalovirus was of the greatest importance for colon cancer.

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