NEW OPPORTUNITIES FOR THE PREVENTION OF PREECLAMPSIA

One of the main directions of personalized medicine in obstetrics, today, is the search for effective predictors of the development of preeclampsia, which will reduce the frequency of this complication of pregnancy and childbirth. One of these possibilities is prenatal screening "Predictor PE" in the early detection of women at risk of developing PE. To achieve this goal, the efficacy of early screening for prognosis of PE was studied in 50 women according to the obtained data of serum markers and the outcome of pregnancy and childbirth observed in the Republican Medical Genetic Consultation in Almaty. It was noted that the technique has the highest diagnostic sensitivity (DR – 84%) in terms of predicting PE with early onset, while for late PE this indicator is lower (DR – 74%).
The introduction of the Predictor PE test for predicting the development of PE in antenatal clinics will reduce the frequency of unreasonable diagnoses of PE and its treatment, and improve the quality and level of prenatal care.

1. Святова Г.С., Кирикбаева М.С., Байысбекова А.С. Эффективность раннего пренатального скрининга преэклампсии. и ӀӀ VIII региональный научный форум «Мать и дитя». – Алматы, 2018. – С. 56-57.

2. Анализ причин смерти беременных, рожениц и родильниц в Республике Казахстан за 2018 г. АО «Научный центр Акушерства, гинекологии и перинаталогий. - Алматы, 2019. – 256 с.

3. Veronica Hackethal, MD. Simple New Urine Test for Preeclampsia Could Saue Vany Lives. Medscap Ob Syns Womens Health. - 2016.

4. H. Zeister, E/Liurba, F.Chantraine et al. Predictive Value of the S Fet-1/PLGF Ratio in Women with Suspectiol Preeclampsia // The New England Journal of Medicint. - 2016.

5. Ким Т.В., Каюпова Л.С. Новые предикторы раз- вития преэклампсии // Акушерство, гинекология и пе- ринатология. – 2019. - №1-2. – С. 125-126.

6. Курцер М.А., Шаманова М.Б., Синицина О.В., Николаева А.А., Дедловская А.И., Самсонова М.А. Клиническое обоснование определения соотношения S Fet-1/PLGF с целью раннего выявления и оценки степени тяжести преэклампсии. - Акушерство и гинекология 2018;11: 114-20.