Empirical therapy in men with impaired reproductive function who underwent microsurgical subinguinal varicocelectomy

   In Kazakhstan, male infertility accounts for 30 % to 45 % of cases. The pathogenesis of fertility decline in patients with varicocele is based on thermal exposure, which is often accompanied by oligozoospermia and asthenozoospermia. One of the most frequently used methods of treatment in the postoperative period in patients with impaired fertility and varicocele, antiestrogens are used, since they enter into the feedback of sex steroids at the level of the hypothalamus and pituitary gland, increasing the production of endogenous gonadotropin-releasing hormone by the hypothalamus and, respectively, LH and FSH by the pituitary gland.

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