Endometriosis on the background of chronic brucellosis (a series of clinical cases)

The relevance of the presented clinical observations is due to the rarity of the development of cutaneous forms of extragenital endometriosis occurring against the background of chronic infectious diseases, in particular brucellosis. Brucellosis is characterized by immunopathological reactions that contribute to impaired immune surveillance and the maintenance of chronic inflammation, creating conditions for the progression or atypical course of endometriosis. The number of descriptions of cutaneous forms of endometriosis in the background of chronic infections is extremely limited in the available literature, which makes the presented cases a valuable contribution to clinical practice and deepens the understanding of the immunopathogenesis of the disease.

A series of clinical cases:

Diagnosis of 1 case. The diagnosis is primary chronic brucellosis. Subcompensation. Osteochondrosis, spinal spondyloarthritis of the cervical, thoracic and lumbosacral spine with radicular syndrome. Osteoarthritis of the knee, small hands and feet, talus-calcaneus-navicular joints. Spastic colitis. Uterine fibroids. Extragenital endometriosis.

Diagnosis of the second case. Primary-chronic brucellosis, subcompensation. Small-focal myocarditis. Degenerative-dystrophic changes of the lumbar spine. L2-L4 spondylosis. L1 spondylitis with a small leak. Osteochondritis L2-L3, L3-L4, L4-L5, L5-S1. Osteoarthritis of the knee and small bones of the joints. Phlebitis. Vegetative vascular dystonia. Polyarthroneuromyalgia. Endometriosis. Salpingooophoritis. Ovarian cyst on both sides.

Concusions. The presented clinical cases demonstrate the development of external extragenital endometriosis. The leading clinical syndrome was pain syndrome, manifested as secondary dysmenorrhea.

The chronic infectious process led to a dysfunction of the immune system, resulting in the dissemination of endometriodic heterotopias into various organs.

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